when it comes to nutrition and bone health,there's quite a bit written about alkaline diets, a diet that is high in fruits and vegetablesand low in saturated fats, but what i'd like to talk about today, specifically, is somerecent research that looked at an important mineral and an important vitamin when it comesto bone health. so let's start with vitamin d. in the spring of 2010, the general of theamerican medical association published an article that had just over 2,000 women inthe average age 76 years of age and they were given mega doses of vitamin d once a yearover a three to five year period. so, mega doses, 500,000 international units, once ayear. what this study found, was that these
woman actually had an increased fracture risk.the medical advisory committee from osteoporosis canada had a couple of theories in regardsto the increased risk of fractures. one of them was that the enzymes that are neededto break down the active vitamin d were being produced at too great a level. another theorywas that people were feeling so good about having all that vitamin d and their musclefunction was working so much better, that they were all of a sudden just being thatmuch more active and that might have increased their risk of fractures. the main outcomeof this study was that although vitamin d is a fat-soluble vitamin, we shouldn't berecommending to our clients that they take all their vitamin d in one day of the year,but rather, getting it the way nature intended,
a little bit every day. so, the recommendationsin canada still stand between 800 and 2,000 international units a day. as far as calcium, there is a study that waspublished in the british medical journal in the summer of 2010. it was actually a metaanalysis. and this meta analysis looks specifically at calcium supplementation alone in womenand it was quite alarming because they found that women that were taking high calcium supplementationhad a significant increased risk of heart attacks. and so the recommendation is thatcalcium should not be taken alone because vitamin d helps with the absorption of calcium.another recommendation in canada was that the recommended levels of 1,500 milligramsper day for the adult population over the
age of 50 was reduced to 1,200 milligramsa day. and so far, as pharmaceuticals, as healthcareprofessionals, it's very important for us to be aware of the different medications thatour clients are on and the effect that it has, when we're talking about osteoporosis,on their bone health. and so, there are a lot of bisphosphonates. if you listen to anyof the commercials that ran the six o' clock news, you're going to be bombarded by commercialson different bisphosphonates and not all bisphosphonates are created equal. some bisphosphonates protectagainst vertebral fractures, some against non-vertebral factors and some against both.now, all these bisphosphonates are not created equal and so, it's important that you be awareand that's one thing we go into in more detail
in the melioguide course, is the type of bisphosphatesthat are available on the market. at the 2010 american society for bone andmineral research that was held in toronto, there was an interesting study that was presentedlooking at bisphosphonates and their ability to stay within the skeleton and slowly releaseover time in individuals who had been on bisphosphonates for some time. in this study, they found thatrisedronate was a bisphosphonate that did not stay in the system, so they did not detectany risedronate in the urine, even after 19 months of cessation. alendronate, on the otherhand, did stay within the body. so within these types of bisphosphonates, some of yourclients can go on what they call drug holidays, whereas some cannot. tomorrow, i'm going toshare with you some stories on how myself
and other health professionals integrate melioguideinto our practice and how it can help you in your practice.